| Purpose of derivatization |
 | Improved volatility, better thermal stability or a lower limit of detection in GC |
 | Prerequisite: quantitative, rapid and reproducible formation of only one derivative |
 | Halogen atoms introduced by derivatization (e.g., trifluoroacetates) for specific detection (ECD) with the advantage of high sensitivity |
 | Influence of elution orders and fragmentation patterns in MS by a specific derivatization |